Lactate clearance as a target of therapy in sepsis: A flawed paradigm
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چکیده
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assessment of the effect of honey as a topical therapy for intra oral wound healing in rat.
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Background: The Surviving Sepsis Campaign international consensus guidelines recommend early resuscitation to optimize oxygen delivery. Although the best measure of oxygen delivery is debated, the published protocol utilized central venous oxygen saturation (ScvO2) of >70%. Serum lactate has been shown to prognosticate outcome, with higher levels being associated with worse morbidity and mortal...
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We sought to determine (a) if early lactate clearance is associated with improved survival in emergency department patients with severe sepsis and (b) the concordance between central venous oxygen saturation (ScvO2) optimization and lactate clearance during early sepsis resuscitation. Within a multicenter shock research network that uses quantitative resuscitation for severe sepsis, we analyzed...
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ژورنال
عنوان ژورنال: OA Critical Care
سال: 2013
ISSN: 2052-9309
DOI: 10.13172/2052-9309-1-1-431